Domustyche Guest House

5 Via Sebastiano Grandis, Esquilino, Rome, Italy - Nearby popular attractions
9.5/10 · 116 reviews

Featuring Wi-Fi throughout the property, the 4-star Domustyche Guest House Rome sits only 0.9 miles from Ancient Roman ruins.

Location

This Rome guest house lies in the Esquilino district of Rome, about 25 minutes by foot from the hulking ruins "Baths of Caracalla". Perfect for those who seek new knowledge, the Italian Sapienza University of Rome is 1 mile from the hotel. The monumental cathedral "Basilica di San Giovanni in Laterano" is also right near the Domustyche Guest House Rome. The accommodation is around 10 minutes by foot from Manzoni subway station and is also around a 10-minute drive from the aqueduct-fed rococo Trevi Fountain. Ciampino airport is 10 miles away from this Rome hotel.

Rooms

The rooms at the Domustyche Guest House include an air conditioner, as well as media facilities like a flat-screen TV with satellite channels. Fitted with tea and coffee-making facilities, the rooms also come with a writing table and a cabinet. A separate toilet and a shower, along with a hairdryer and a shower cap, are provided in the bathrooms. Also, the rooms with views of the urban are provided for guests' comfort.

Food & Drinks

European cuisine is offered at Osteria La Sol Fa, situated just moments from Domustyche Guest House.

Why choose Domustyche Guest House Rome

Select room

  • Rooms with air conditioning

  • Free Wi-Fi throughout property

  • Shared kitchen available for guests

  • Family rooms to accommodate groups

Main amenities

  • Wi-Fi

  • Child-friendly

  • Air conditioning

  • No pets allowed

General
  • Wi-Fi
  • Child-friendly
  • Air conditioning
  • No pets allowed
1/13

Internet

  • Wi-Fi

Parking options

  • Parking

Property services

  • Security
  • Luggage storage
  • Housekeeping

In the kitchen

  • Shared kitchen
  • Electric kettle

For kids

  • Cots

In the rooms

  • Air conditioning
  • Heating
  • Tea and coffee facilities

In the bathroom

  • Free toiletries

Devices

  • Flat-screen TV

General facilities

  • No smoking on site
  • Lift
  • Smoke detectors
  • Fire extinguishers
  • Key access

Pets

  • No pets allowed

Important information

Check-in:
from 14:00 until 22:00
Check-out:
until 10:00
License number35398,IT058091B45RY32CGL

Enter dates to see availability

From USD 147 per night
Check-in 17 May 2026
Check-out 18 May 2026
Guests 2 guests

Adults:

2

Children:

0
All rates verified
How we verified prices Our team regularly checks prices to make sure you see the lowest available rates. We compare them with hotel prices and other providers. If discounts or promotions appear, prices on our site are updated accordingly.

Rooms

Photos of Domustyche Guest House Rome

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Domustyche Guest House
Domustyche Guest House
Domustyche Guest House
Domustyche Guest House

Domustyche Guest House Rome

Hotel offering convenient access to historical sites and public transport

Location of Domustyche Guest House Rome

5 Via Sebastiano Grandis, Esquilino, Rome, Italy

 -  Nearby popular attractions
Attractions
Great restaurants
Transportation

Places nearby

    Guest reviews of Domustyche Guest House Rome

    9.5 Exceptional
    116 reviews

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    100% Verified Reviews
    Enter dates to see availability
    From USD 147 per night
    Check-in 17 May 2026
    Check-out 18 May 2026
    Guests 2 guests

    Adults:

    2

    Children:

    0
    All rates verified
    How we verified prices Our team regularly checks prices to make sure you see the lowest available rates. We compare them with hotel prices and other providers. If discounts or promotions appear, prices on our site are updated accordingly.
    Check-in & out
    17 May 2026
    —
    18 May 2026
    Guests
    2 guests
    Check availability
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    Important information
    Domustyche Guest House
    Check-in:
    from 14:00 until 22:00
    Check-out:
    until 10:00
    License number35398,IT058091B45RY32CGL